Approach to correction of apoptotic disorders in children with early diabetic nephropathy
نویسندگان
چکیده
Diabetic nephropathy is a disease characterized by pathological changes in glomeruli that lead to the development of albuminuria, hypertension, and decline renal function. Prominent detected apoptosis controlling factors, i.e. BcL-xL caspase-3 require search for additional non-toxic therapeutic interventions, antioxidants, anti-apoptotic effectors addition glycemic control, hypertension management, as well albuminuria. The present study included forty-four
منابع مشابه
Diabetic nephropathy in children.
It is estimated that among 100 million European children aged 0–14 years, some 10 000 will develop insulin-dependent diabetes mellitus (IDDM) each year. Within a subset of 10–30% of IDDM patients who will ultimately develop diabetic nephropathy (DN), the earliest stages of disease can be detected within the first 4–5 years after diagnosis w1–3x. We present the risk factors for the development, ...
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15 صفحه اولEarly Diabetic Nephropathy
OBJECTIVE Diabetic nephropathy (DN) is a major cause of mortality in type 1 diabetes. Reduced insulin sensitivity is a well-documented component of type 1 diabetes. We hypothesized that baseline insulin sensitivity would predict development of DN over 6 years. RESEARCH DESIGN AND METHODS We assessed the relationship between insulin sensitivity at baseline and development of early phenotypes o...
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ژورنال
عنوان ژورنال: Journal of advanced pharmacy education and research
سال: 2022
ISSN: ['2249-3379']
DOI: https://doi.org/10.51847/g6i3231jnm